Road trip from Matthews to Hartsville

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Find out how many hours from Matthews to Hartsville by car if you're planning a road trip. If you want to explore small towns along the way, get a list of cities between Matthews, NC and Hartsville, TN. Looking for alternate routes? Explore all of the routes from Matthews, NC to Hartsville, TN. Compare the flight distance to driving distance from Matthews, NC to Hartsville, TN, or check for a bus or train from Matthews, NC to Hartsville, TN. Calculate the total cost to drive from Matthews, NC to Hartsville, TN. Or find out if it's better to fly or drive from Matthews, NC to Hartsville, TN?